For the second time, Lionel Messi might not play for Argentina in their next World Cup qualifier game against Paraguay.

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The leader of Argentina scored in the first game, a 1-0 win over Ecuador. But he missed the 3-0 win at Bolivia last month because of muscle pains that have kept him out of several MLS games for Inter Miami.

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The World Cup winners will play Paraguay at home on Thursday in Buenos Aires.

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